Alzheimer’s, Parkinson’s, Huntington’s, multiple sclerosis, and Lou Gehrig’s are neurodegenerative diseases. Neurodegeneration refers to the malfunctioning or loss of neurons. Unlike many cells in the rest of the body, neurons are not readily regenerated. Therefore, excessive neuron damage or loss can have devastating effects on an individual. Neurodegeneration can result from stroke, heart attack, head and spinal cord trauma, and bleeding in the brain. Although each disease or injury has its own peculiar characteristics, many affect middle aged or older people, progress slowly over time, and result in premature death. Neuronal death begins long before an individual experiences any symptoms and the symptoms are only recognized when many cells have died and specific areas of the brain have been weakened to the extent they can no longer function properly.
Prevalence of Alzheimer’s Disease
Alzheimer’s affects about 10% of the population over 65-years old and about 40% of the population over 80-years old. On June 12, 2008, the Centers for Disease Control and Prevention reported that Alzheimer’s disease is now the sixth-leading cause of death in the United States, surpassing diabetes. As many as 5.2 million people in the United States are living with Alzheimer’s. Approximately 10 million baby boomers will develop Alzheimer’s in their lifetime. The cost of caring for people with the disease in US is more than $148 billion each year. This epidemic has enormous implications for society, in terms of both human suffering and monetary cost.
Advancing age is the number one risk factor for developing this condition. One out of eight people over the age of 65 has Alzheimer’s disease, and almost one out of every two people over the age of 85 has got it. The probability of being diagnosed with Alzheimer’s doubles every five years after age 65. The mechanisms underlying the origin and the events responsible for the progression of the disease remain elusive and drugs developed for Alzheimer’s disease have demonstrated no clinically significant effects.
- Memory loss – forget more often and unable to recall recently learned information.
- Difficulty performing familiar tasks – prepare a meal, place a phone call or play a game.
- Problems with language – forget simple words or make speech or writing hard to understand.
- Disorientation to time and place – get lost in a familiar neighborhood.
- Poor judgment – dress inappropriately or give away large sums of money to strangers.
- Problems with abstract thinking – have difficulty performing complex mental tasks.
- Misplacing things – put things in unusual places such as an iron in the freezer.
- Changes in mood or behavior – show rapid mood swings without apparent reason.
- Changes in personality – become extremely confused, suspicious, fearful or dependent.
- Loss of initiative – become very passive, sitting in front of the TV for hours or sleep more than usual.
- Inflammation and Alzheimer’s Disease
Over the past 15 years, accumulating evidence supports the importance of inflammation and oxidative stress in the progression of neurodegenerative diseases. The brain is populated by microglia and astrocytes, resident inflammatory cells capable of producing almost all of the same cytokines, chemokines, growth factors, enzymes, and free radicals as their counterparts in other systems of the body.
When the brain is injured or infected, microglia and astrocytes produce inflammatory mediators. Normally, this response shuts down when the injury or infection is over. But in neurodegenerative diseases like Alzheimer’s, these inflammatory cells are highly activated and produce too much cytokines to try to repair the damage. These inflammatory cytokines have been shown to promote neuronal dysfunction and premature death of neurons. Several clinical studies have revealed supporting evidence that elevated levels of inflammatory biomarkers are associated with increased incidence of Alzheimer’s disease.
Treatment and Prevention:
There is no cure for Alzheimer’s disease. Efforts to find a cure for this condition have been disappointing. The patients are treated for their associated risk factors, which include high cholesterol, high blood pressure, and diabetes. Other treatments are available, which offer relatively small symptomatic benefit.
While oxidative stress causes neuron damage, there is considerable doubt as to whether antioxidant supplementation is beneficial, and if so, which antioxidant(s) are beneficial and in what amounts. To date, some studies have suggested antioxidant supplements have health benefits, other large clinical trials did not detect any benefit for the formulations tested.
Success of preventive strategies has been noticed. Studies indicate that non-steroidal anti-inflammatory drugs (NSAIDs) delay the onset and lower the risk of this condition. Prevention strategies appear to work the best only if begun long before the symptoms of overt Alzheimer’s appear. Long-term NSAIDs users, however, are exposed to dangerous side effects such as gastrointestinal bleeding and increased risk of heart attack and stroke.
Natural Anti-inflammatory Remedies:
To fight inflammation without the side effects of NSAIDs, consumers and medical professionals are looking for safer alternative anti-inflammatory products.
Many natural remedies are readily available for relief of symptoms related to Alzheimer’s and neurodegenerative diseases. FlameEz-Memory, however, is the only natural memory supplement that helps remove inflammatory toxins, the most important contributing factors to neuronal damage and memory loss. Using the safest natural antiinflammatory ingredients in a proprietary combination, FlameEz-Memory is designed to deliver unique benefits to Alzheimer’s sufferers.
For individuals who are at risk for Alzheimer’s disease or neurodegenerative diseases, balancing inflammatory response may be the only effective prevention strategy. Because there is no coming back from neurodegeneration, control of inflammation is more than important, it is VITAL!
Hebert LE, et al. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol. 2003;60:1119?1122.
Lee ST. Kim M. Aging and neurodegeneration. Molecular mechanisms of neuronal loss in Huntington’s disease. Mechanisms of Ageing & Development. 2006;127:432-5.
Lleó A, et al. Current pharmacotherapy for Alzheimer’s. Annu Rev Med. 2006;57:513-533.
Hüll M, et al. Disease-modifying therapies in Alzheimer’s. Drugs. 2006;66:2075-2093
Akiyama H, et al. Inflammation and Alzheimer’s. Neurobiol Aging 2000;21:383–421.
McGeer PI, et al. Inflammation and the degenerative diseases of aging. Ann NY Acad Sci. 2004;1035:104-116.
Watson GS, Craft S. Insulin resistance, inflammation, and cognition in Alzheimer’s Disease: Lessons for multiple sclerosis. J Neurological Sciences 2006;245:21– 33
Tuppo EE, Arias HR. The role of inflammation in Alzheimer’s. Internat J Biochem Cell Biol. 2005;37:289-305.
McGeer PI, McGeer EG. Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve. 2002;26:459-470.
Schmidt R, et al. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol 2002;52:168–74.
Koistinaho M, et al. Interactions between Alzheimer’s disease and cerebral ischemia—focus on inflammation. Brain Res Brain Res Rev 2005;48:240 –250.
Arvanitakis Z, et al. Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function. Arch Neurol. 2004;61:661–666.
Diet food could be something that irritate quite a number of people given that they may think that they will not be able to eat as they wish and are forced to only consume such the food for their health and weight loss program. As a matter of fact, you may find out that your foodstuff could also be something fun to enjoy and taste, depends on how your nutritionist arrange your food.
In general, it is really good to support the healthy lifestyle. It is not only for the elderly, or the patients who suffer from certain disease. Diet food is suggested for everyone who wants to prevent their selves from the attack of the serious disease like heart attack or stroke from the medical guide site. Usually, it will be made of organic ingredients, such as organic rice, organic vegetables, organic spices, and more. Fruits are included in the menu of the program too. The importance of vegetables will also make the foodstuff contents more vegetables rather than meat. If you really want to have meat, the white one will be better than the red one. If possible, to eat like those vegetarian people, and you will experience the healthy body that has been experienced by those vegetarian people.
Delicious and Healthy
Just look at your vegetarian friends. They have their diet plan for example south beach diet food lst out of the meat stuffs, but it does not mean that they cannot taste the taste and the sensation of the meat. They could have the meat made from bean, which is processed in such a way that resulted exactly like meat. Therefore, you do not have to be afraid that the diet will torture you, especially if you used to be culinary lovers. For the longer life, it is always good to choose a diet instead of the junk food. Lots of restaurants are coming with the diet plan to fulfill the demand of the people upon the healthy food. If you cannot find any of the specific diet foodstuff on the menu, choosing the steamed or baked one instead of the fried or grilled one is would do you good. In recent times, where countless numbers of people are getting more and more aware of healthy food for their healthy and longer life, this type of food has become an alternative to choose to help them achieve such an ultimate purpose. As a matter of fact, you might be surprised to find out that there are a lot of healthy foods available for us to choose of which taste is absolutely delicious.
The Best One From Home
The best food for your plan will be found at home, since you are able to find the best ingredients, to control the cooking process, and to measure the amount of the spices. You can also make experiments to create the most delicious one. You can replace the cooking oil with olive oil, steam the fish instead of fry it, and boil the vegetables in appropriate times so that it will not be too well done. The half done boiled vegetables will give you more nutrition that completes your regimen best.
Diabetes has become the common ailment which may have distribute widely on the list of peoples all over the world. It can be the real reason for the illness like excess fat physique and chubbiness along with less fat loss up. Individuals having diabetes encounters health problems just like failure regarding pancreas with the body as well as struggles to use on producing chemicals which usually needed for transferring the blood sugar throughout one’s body. That’s why individuals suffered from diabetes mellitus would not have adequate energy movement within their system and also suffering from several medical problems. You can discover a number of people endured through all forms of diabetes possibly even as part of your family also. In such cases you shouldn’t have to get concerned because there are quite a few blood tests designed for diabetes which is often very helpful to enable you to monitor and detect the health concerns. Here you can find some blood tests types created for Diabetes.
Regarding Diabetes, the typical blood tests done to confirm it is known as finger prick blood sweets screening which is often performed by way of nursing homes, treatment centers as well as laboratories. This can be a most typical blood testing sort which often provided everywhere you go. To train on finger prick blood glucose screening a small amount of blood is collected from a finger suggestion via a small needle to determine the blood sugar. Inspecting the blood sugars can be performed by having a monitoring program which shows the specific way of measuring level of blood sweets inside the examined blood vessels. Currently many blood tests devices released for this certain purpose which usually possibly lets you analyze your current blood all on your own.
A different type of blood tests with regard to Diabetes will probably be random blood tests. This can be done based on the doctor’s support at several monthly or perhaps annual times. Not just like finger prick blood glucose screening test this specific random blood assessment assesses the particular blood and implies more than the existence of all forms of diabetes which is not important for the all forms of diabetes patient to obtain this blood test over and over again per year.
Carbs and glucose tolerance test has become the blood tests sorts done for diabetic issues. This type of blood check-up shows the amount the person will be endured via diabetes. Blood sugar tolerance test might be conducted in early stages the day while the blood provides sufficient time in order to rotate the actual glucose content material of the blood all over the country body. For having the actual blood tests you’ll want to drink an increased sugar written content drink as being a soda prior to the blood examination. It will help the particular physicians to hold track of your acceptance with the sugar chemical by your system. This type precisely pointed out your diabetes volume of your entire body.
Glycated hemoglobin test is carried out for calculating the right amount associated with sugar inside blood for a selected period of time. Generally several sweets compound keeps with the bodies hemoglobin blood vessel tissues for a few months. This type of blood screening shows the particular accurate quantities of blood sugar which is often very well suited for treating you are not diabetes.
One must take of his heart very much as it is the vital organ of our body which plays an important role in our body. If your heart encounters any kind of problem then you are in danger. You have a high risk to your life as the heart problems are killer ones. About 1.1 million Americans face the heart problems symptoms and 50 % of them die due to the heart attack. Heart problems are fatal and therefore you must neglect the warning signs of heart problems. The death of the patients in heart attack is due to the ventricular fibrillation of the heart. The patient is dead before he/she reaches to an emergency room. Lucky are those who had a strong prognosis of heart problem symptoms. They survive from the major heart attacks also. We have so many advance technologies that the heart attack problem can be resolved if the symptoms are diagnosed on time. Diagnosis of heart problem symptoms instantly let the patient get treated with heart attack preventive medicines and their heart muscles suffer less damage.
The people who die in emergency room are unlucky as they suffer from serious damage to the tissues of the heart in the beginning. Treatments like angioplasty and angiography are so advanced that in few minutes the blocked arteries are opened quickly and blood circulation is restored again. The blood restoration must be done within twenty minutes of heart attack any delay in the procedure will cause to death of the patient.
Knowing the warning signs of heart problems is important for all. Early detection of heart problem symptoms will help you in seeking fast medical treatment. Heart attack is not as dramatic as we all often see in movies.
Weight loss programs, occupies the mind of vegetarians, in the same way as it is an issue with the non-vegetarians. However, weight loss for vegetarians is less difficult as compared to non-vegetarians. Research proves that it is easier for people consuming a low fat, vegetarian diet to lose weight as compared to a non-vegetarian diet.
Scientific research indicates, curses like being overweight or obese, are less common among vegetarians than among non-vegetarians. A study involving about 55000 Swedish women pronounces 40% non-vegetarians to be obese while only 25% to 29% vegetarians reached the mark of obesity. Throughout the world, the numbers of vegetarians suffering from grievous diseases arising from obesity, like diabetes, heart disease or high blood pressure is low.
Usually, vegetarian diets consisting of low fat and cholesterol include more fiber. Following a vegetarian diet makes oneself enjoy generous helping of whole grains, fruits, vegetables and other healthy products which help vegans lose weight, without leading to a feeling of being hungry. Though vegetarian diets offer lower calorie values, they do not always guarantee health. Some vegetarian foods are as fattening as their non-vegetarian counterparts. As a matter of fact, some vegetarian dishes and products contain more fat as compared to the meat or fish based ones. Consumption of these foods or vegetarian fast foods can also lead to a rapid gain of weight. A balanced diet is essential in order to maintain proper weight and control obesity.
Breakfast being first meal of the day, must contain about 350 to 450 calories. Intake of about 400 to 500 calories is sufficient for lunch and dinner while snacks need must consist of at least 100 to 200 calories. A daily diet must comprise of grains, vegetables, fruits, dairy or milk products and dry beans, nuts, seeds, etc.
As vegetarians do not consume high protein products like meat and fish, they need to substitute it by products like milk, soy bean or peas. In case of digestive problems, dairy products need to be replaced by soy based replacements of milk, cheese or yogurt. Vegetarians, while choosing food products, must also ascertain that the products are packed with Vitamin D, Calcium or Riboflavin. Consumption of whole grain products is also advised since it keeps hunger at bay, thereby playing a significant role in weight loss programs.
Simply giving up meat does not ensure weight loss since a large number of vegetarian products are packed with calorie as they are rich in either sugar or fat contents. A balanced diet is essential to check fat. Regular fat intake should not be more than 30 to 35 grams. High calorie dairy products like cheese and mayonnaise must be avoided. Regular servings of carbohydrate like rice, wheat bread, wholegrain cereal and oats should be included in the diet since these foods induce a feeling of being full leading to the avoidance of high calorie foods.
Planning ahead of the meal works out well since it gives the time to think over, thereby leading to better choices than last minute decisions. Lastly, vegetarians must also be cautious of too low a level of nutrition, arising from dieting, as this slows down the metabolic rate, and that is a step towards weight gain and not weight loss!!!
Minimalism is the design or style in which the simplest and fewest elements are used to create the maximum effect. A minimalist design involves the concepts of simplicity, functionality, and efficiency within a given environment, in order to optimize the use of a space and have less visual clutter. There are many different styles of minimalist design based on the minimalist lifestyle level one adopts. I personally prefer a rational minimalist interior with functional furniture and accents that reflect my style. In my opinion, minimalist design can be accomplished however you choose whether it is an absolute minimally designed space with only a bed and table and chair, or a space with a few high quality pieces and carefully planned accents, or it can simply be your current home design without the useless clutter lining the shelves. The purpose of my blog is to help proivde you with functional design ideas for whichever minimalist style you prefer to incorporate into your living environment.
I am an interior architect and designer fresh out of school and working my way to becoming registered. I stumbled upon the idea of minimalism while researching ways to control my budget due to all these lovely student loans. As I’ve made the transition I’ve discovered that minimalism equals more space, less stress, and endless possiblities for beautiful design. mnmize is a blog about the benefits of minimalism not only within your life and budget, but it’s impact on your living space – how to make the transition and design minimally and effectively.